反应详情

To a solution of 4-(2′,4′-dichloro-4-ethylbiphenyl-3-yl)-2,2,6,6-tetramethylpyran-3,5-dione (0.220 g, 0.525 mmol) in dry chloroform (4 ml) is added sulfuryl chloride (0.085 ml, 1.05 mmol), followed by stirring at room temperature for 4 hours. After dilution with diethyl ether (150 ml) the organic phase is washed with saturated sodium carbonate (150 ml) then dried over magnesium sulphate and the filtrate concentrated in vacuo to afford 4-chloro-4-(2′,4′-dichloro-4-ethylbiphen-3-yl)-2,2,6,6-tetramethylpyran-3,5-dione (0.229 g, 96%) as a white solid.

1. washAfter dilution with diethyl ether (150 ml) the organic phase is washed with saturated sodium carbonate (150 ml)
2. dry with materialthen dried over magnesium sulphate
3. concentrationthe filtrate concentrated in vacuo