HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 5-Iso-propylidene-2-thiohydantoin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 5-(Propan-2-Ylidene)Imidazolidine-2,4-Dione | HCID 336450 | — |
| Reactant | 2-Thiohydantoin | HCID 1274030 | — |
| Solvent | Piperidine | HCID 8082 | — |
| Product | 5-Iso-propylidene-2-thiohydantoin | HCID 20385919 | — |
Reaction Steps
Doyle et al, J. Chem. Soc. 1955, 2265-73 (Chemical Abstracts 1956, 50, 8602g at 8603b) teach the preparation of 5-iso-propylidenehydantoin via the reaction of acetone with 2-thiohydantoin in piperdine to yield 5-iso-propylidene-2-thiohydantoin which is then desulfurized with chloroacetic acid to yield 5-iso-propylidenehydantoin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04175198 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-802fce0a0d7b4bb88b9d3439cdc34b2b |
| Source note | uspto-grants-1979_11 |