HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 468416Generated: October 30, 2026
Dimethylacetamide → E-ethyl 5-(2-(dimethylamino)vinyl)-2,4-dinitrobenzoate
https://huagongshe.com/reaction/468416
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Reactant | Ethyl 5-methyl-2,4-dinitrobenzoate | HCID 15184632 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | E-ethyl 5-(2-(dimethylamino)vinyl)-2,4-dinitrobenzoate | HCID 10590973 | 32.3% |
Reaction Steps
A mixture of ethyl 5-methyl-2,4-dinitrobenzoate (39 g, 0.15 mol) and DMA (32 g, 0.27 mol) in DMF (200 mL) was heated at 100° C. for 5 h. The mixture was poured into ice water and the precipitated solid was filtered and washed with water to afford (E)-ethyl 5-(2-(dimethylamino)vinyl)-2,4-dinitrobenzoate (15 g, 28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08623905B2 |
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| Source dataset | uspto-grants-2014_01 |
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| ORD ID | ord-2b1554be68f14fbab948caf7513d4077 |
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| Source note | uspto-grants-2014_01 |
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