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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 468532Generated: October 29, 2026

2-(tert-Butyl)-5-nitro-1H-indole → (R)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-1H-indol-5-yl)-1-(3,4-dihydroxyphenyl)cyclopropanecarboxamide

https://huagongshe.com/reaction/468532

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(tert-Butyl)-5-nitro-1H-indoleHCID 10584913—
Reactant1-(3,4-Dihydroxyphenyl)cyclopropanecarboxylic acidHCID 59129368—
Product(R)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-1H-indol-5-yl)-1-(3,4-dihydroxyphenyl)cyclopropanecarboxamideHCID 59129352—

Reaction Steps

(R)—N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-1H-indol-5-yl)-1-(3,4-dihydroxyphenyl)cyclopropanecarboxamide was prepared using an experimental procedure similar to Example 72 from 1-(3,4-dihydroxyphenyl)cyclopropanecarboxylic acid and 2-tert-butyl-5-nitro-1H-indole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08623905B2
Source datasetuspto-grants-2014_01
ORD IDord-ff0e7819ea5d4b1b8e7d2316cf3ac2ea
Source noteuspto-grants-2014_01