Water → Laurolactam

HRID 468533Notes

Reaction equation

HRID 468533 reaction equation
[C:1]1(=[N:13]O)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH2:15]>>[C:1]1(=[O:15])[NH:13][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 962WaterHCID 136762Cyclododecanone, oxime

Product 1

HCID 13690Laurolactam

Procedure

For example, in terms of treatment of cyclododecanone oxime after the reaction, water is added to a reaction mixture of the Beckmann rearrangement reaction, and the resulting mixture is extracted with an organic solvent and the solvent can be evaporated to give laurolactam, which can be further separated and purified by distillation, crystallization and the like.

Workup

  1. additionis added to a reaction mixture of the Beckmann rearrangement reaction
  2. extractionthe resulting mixture is extracted with an organic solvent
  3. customthe solvent can be evaporated

Sources & evidence

ORD record
ord-fcd82ee021104813a0472a7ebf23d785
Source dataset
uspto-grants-2014_01
Patent number
US08624021B2

Reaction notes

Loading…