HRID468577

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1(C)C(=O)N(c2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C(=O)N1CCCCCN1C(=O)N(c2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C(=O)C1(C)C

HCID46937259

未命名化合物

结构：CC1(C)C(=O)N(c2ccc(N)c(C(F)(F)F)c2)C(=O)N1CCCCCN1C(=O)N(c2ccc(N)c(C(F)(F)F)c2)C(=O)C1(C)C

HCID49764091

未命名化合物

结构：Cc1cc(N2C(=O)N(CCCCCN3C(=O)N(c4ccc([N+](=O)[O-])c(C)c4)C(=O)C3(C)C)C(C)(C)C2=O)ccc1[N+](=O)[O-]

HCID49764092

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(N2C(=O)N(CCCCCN3C(=O)N(c4ccc(N)c(C)c4)C(=O)C3(C)C)C(C)(C)C2=O)ccc1N

HCID66752400

未命名化合物

收率 69%

PROCEDURE

实验过程

The experimental protocol used is the same as that described for the synthesis of the compound of Example 8 starting from the compound of Example 10, which replaces the compound of Example 2. The expected compound is obtained in the form of a white foam with a yield of 69%.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-108e6c62b0044c3f832bf5962e5b6cc0
来源数据集: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08624037B2
来源说明: uspto-grants-2014_01

反应 SMILES

[CH2:1]([N:26]1[C:30]([CH3:32])([CH3:31])[C:29](=[O:33])[N:28]([C:34]2[CH:39]=[CH:38][C:37]([NH2:40])=[C:36]([C:41](F)(F)F)[CH:35]=2)[C:27]1=[O:45])[CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[C:10]([CH3:12])([CH3:11])[C:9](=[O:13])[N:8]([C:14]2[CH:19]=[CH:18][C:17]([NH2:20])=[C:16]([C:21](F)(F)F)[CH:15]=2)[C:7]1=[O:25].C(N1C(C)(C)C(=O)N(C2C=CC([N+]([O-])=O)=C(C)C=2)C1=O)CCCCN1C(C)(C)C(=O)N(C2C=CC([N+]([O-])=O)=C(C)C=2)C1=O.C(N1C(C)(C)C(=O)N(C2C=CC([N+]([O-])=O)=C(C(F)(F)F)C=2)C1=O)CCCCN1C(C)(C)C(=O)N(C2C=CC([N+]([O-])=O)=C(C(F)(F)F)C=2)C1=O>>[CH2:5]([N:6]1[C:10]([CH3:12])([CH3:11])[C:9](=[O:13])[N:8]([C:14]2[CH:19]=[CH:18][C:17]([NH2:20])=[C:16]([CH3:21])[CH:15]=2)[C:7]1=[O:25])[CH2:4][CH2:3][CH2:2][CH2:1][N:26]1[C:30]([CH3:32])([CH3:31])[C:29](=[O:33])[N:28]([C:34]2[CH:39]=[CH:38][C:37]([NH2:40])=[C:36]([CH3:41])[CH:35]=2)[C:27]1=[O:45]