[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol → HCID 67974777, compound

HRID 468903Notes

Reaction equation

HRID 468903 reaction equation
Cl[C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[C:7]([NH:12][C:13]([CH:15]3[CH2:17][CH2:16]3)=[O:14])[N:8]=[CH:9]2)=[CH:4][N:3]=1.CC1(C)C(C)(C)OB([C:26]2[CH:27]=[C:28]([CH2:32][OH:33])[CH:29]=[CH:30][CH:31]=2)O1>>[OH:33][CH2:32][C:28]1[CH:27]=[C:26]([C:2]2[CH:11]=[C:10]3[C:5]([CH:6]=[C:7]([NH:12][C:13]([CH:15]4[CH2:17][CH2:16]4)=[O:14])[N:8]=[CH:9]3)=[CH:4][N:3]=2)[CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 44118236[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanolHCID 86674974HCID 86674974, compound

Product 1

HCID 67974777HCID 67974777, compound

Procedure

The title compound was prepared following a procedure similar to example 162 using N-(7-chloro-2,6-naphthyridin-3-yl)cyclopropanecarboxamide and (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol.

Sources & evidence

ORD record
ord-b2c243eff5ff4591961879b620ce4723
Source dataset
uspto-grants-2014_01
Patent number
US08623889B2

Reaction notes

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