HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Carbonyldiimidazole → HCID 58393288, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-({[(4-Methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxylic acid | HCID 58393097 | — |
| Reactant | HCID 64263172 | HCID 64263172 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 58393288 | HCID 58393288 | — |
Reaction Steps
The title compound was prepared according to general procedure AA using 5-({[(4-Methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)furan-3-carboxylic acid (60 mg, 0.15 mmol), CDI (46 mg, 0.27 mmol), DIPEA (0.134 mL, 0.76 mmol) and N-[4-(2-aminoethyl)benzyl]-2-methylpropan-1-amine (40 mg, 0.14 mmol) in DCE (1 mL). A portion of the crude product was purified using prep method A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623859B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-f57453c57ea643ce9d330428714497be |
| Source note | uspto-grants-2014_01 |