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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469106Generated: October 30, 2026

Trimethylaluminum → HCID 46176236, compound

https://huagongshe.com/reaction/469106

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylaluminumHCID 16682925—
ReactantHCID 58393137HCID 58393137—
ReactantMethyl 5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-1,3,4-oxadiazole-2-carboxylateHCID 67217606—
Solvent1,2-DichloroethaneHCID 11—
ProductHCID 46176236HCID 46176236—

Reaction Steps

The title compound was prepared according to general procedure AT using methyl 5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-1,3,4-oxadiazole-2-carboxylate (30 mg, 0.08 mmol), 1-{4-[(3-methoxyazetidin-1-yl)methyl]phenyl}-N-methylmethanamine (30 mg, 0.14 mmol) and trimethylaluminium (2 M in toluene, 0.08 mL) in DCE (5 mL). A portion of the crude product was purified using prep method D to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08623859B2
Source datasetuspto-grants-2014_01
ORD IDord-8be107d1db564aa186a74a182a56c15b
Source noteuspto-grants-2014_01