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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469133Generated: October 30, 2026

1-((1-Methyl-4-piperidinyl)methyl)piperazine → HCID 178491759, compound

https://huagongshe.com/reaction/469133

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((1-Methyl-4-piperidinyl)methyl)piperazineHCID 2736942—
ReactantTrimethylaluminumHCID 16682925—
ReactantHCID 178470466HCID 178470466—
Solvent1,2-DichloroethaneHCID 11—
ProductHCID 178491759HCID 178491759—

Reaction Steps

The title compound was prepared according to general procedure AT using ethyl 5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-4H-1,2,4-triazole-3-carboxylate (30 mg, 0.08 mmol), 1-[(1-methylpiperidin-4-yl)methyl]piperazine (31 mg, 0.16 mmol) and trimethylaluminium (2 M in toluene, 0.08 mL) in DCE (5 mL). A portion of the crude product was purified using prep method B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08623859B2
Source datasetuspto-grants-2014_01
ORD IDord-97aa4156e1854015953633fec315b57e
Source noteuspto-grants-2014_01