HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((1-Methyl-4-piperidinyl)methyl)piperazine → HCID 178491759, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((1-Methyl-4-piperidinyl)methyl)piperazine | HCID 2736942 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | HCID 178470466 | HCID 178470466 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 178491759 | HCID 178491759 | — |
Reaction Steps
The title compound was prepared according to general procedure AT using ethyl 5-({[(4-methoxy-2,6-dimethylphenyl)sulfonyl](methyl)amino}methyl)-4H-1,2,4-triazole-3-carboxylate (30 mg, 0.08 mmol), 1-[(1-methylpiperidin-4-yl)methyl]piperazine (31 mg, 0.16 mmol) and trimethylaluminium (2 M in toluene, 0.08 mL) in DCE (5 mL). A portion of the crude product was purified using prep method B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623859B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-97aa4156e1854015953633fec315b57e |
| Source note | uspto-grants-2014_01 |