HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4,4-Trifluorobutanoic acid → Tert-butyl 4,4,4-trifluorobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4,4-Trifluorobutanoic acid | HCID 2777085 | — |
| Reactant | Tert-butyl 5,5,5-trifluoropentanoate | HCID 86671369 | — |
| Product | Tert-butyl 4,4,4-trifluorobutanoate | HCID 65710954 | — |
Reaction Steps
Preparation 4A was prepared from 4,4,4-trifluorobutanoic acid (4.99 g, 35.1 mmol) using the general procedure shown for Preparation 1A. Preparation 4A (5.58 g, 80%) was obtained as a colorless oil. 1H NMR (400 MHz, CDCl3) δ ppm 2.47-2.52 (2H, m), 2.37-2.45 (2H, m), 1.46 (9H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629136B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-4a201e87f4864b35a739e765f16cb71e |
| Source note | uspto-grants-2014_01 |