反应详情

26.0 g (70.3 mmol) (1-benzylpiperidin-4-yl)-[2-(5-methoxy-2-nitrophenyl)-ethyl]-amine were hydrogenated with 5.00 g (2.45 mmol) rhodium charcoal (5%, moistened with water) in 350 mL methanol in a 3 bar hydrogen atmosphere for 3 h at RT. The catalyst was removed by suction filtering and the solution was concentrated by rotary evaporation. 23.9 g of residue was obtained, which was immediately reacted further without any further purification.

1. customThe catalyst was removed by suction
2. filtrationfiltering
3. concentrationthe solution was concentrated by rotary evaporation