HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Cyano-5-fluoro-benzoic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Cyano-5-fluorobenzoic acid | HCID 2757963 | — |
| Product | 3-Cyano-5-fluoro-benzoic acid chloride | HCID 21942593 | — |
Reaction Steps
1.65 g (10.0 mmol) 3-cyano-5-fluorobenzoic acid were boiled for 2 h with 7.27 mL (100 mmol) thionyl chloride with stirring. The reaction mixture was evaporated to dryness i. vac. and coevaporated twice with toluene. The residue was reacted further as the crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629137B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-283c3667309b4b41b7d6e7a741c75ffd |
| Source note | uspto-grants-2014_01 |