HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminum(III) Chloride → 6-(2,6-dichloro-pyrimidine-4-carbonyl)-4-methyl-3H-benzoxazol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 2,6-dichloropyrimidine-4-carbonyl Chloride | HCID 11031133 | — |
| Reactant | 4-Methyl-3H-benzooxazol-2-one | HCID 12709336 | — |
| Product | 6-(2,6-dichloro-pyrimidine-4-carbonyl)-4-methyl-3H-benzoxazol-2-one | HCID 58181148 | — |
Reaction Steps
2.75 g (13.0 mmol) 2,6-dichloro-pyrimidine-4-carboxylic acid chloride, 1.94 g (13.0 mmol) 4-methyl-3H-benzoxazol-2-one and 6.93 g (52.0 mmol) aluminium trichloride were heated to 125° C. for 1.5 h with stirring. The mixture combined with ice water and the product precipitated as a solid was suction filtered, washed with water and dried i. vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629137B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-5267ba92f4aa48aa831d8429ee973551 |
| Source note | uspto-grants-2014_01 |