Pyridinium chloride → 4'-(3,4-dimethyl-2-oxo-2,3-dihydro-benzoxazole-6-carbonyl)-4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-3,4,5,6-tetrahydro-2H,1'H-[1,2']bipyridinyl-6'-one

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Reaction Steps

20 mg (0.034 mmol) 1-[6′-benzyloxy-4′-(3,4-dimethyl-2-oxo-2,3-dihydro-benzoxazole-6-carbonyl)-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl]-1,3-dihydro-imidazo[4,5-b]pyridin-2-one in 0.10 g (0.87 mmol) pyridine hydrochloride were kept in a melt for 4 min. After cooling the mixture was purified by preparative HPLC-MS. The fractions containing the product were combined and freeze-dried.

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