HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bms-973013 → HCID 25269459, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bms-973013 | HCID 22293182 | — |
| Reactant | HCID 58181155 | HCID 58181155 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 25269459 | HCID 25269459 | — |
Reaction Steps
0.40 g (1.8 mmol) 1-piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one and 0.18 g (0.60 mmol) 6-(2-chloro-pyridine-4-carbonyl)-3,4-dimethyl-3H-benzoxazol-2-one were stirred overnight in 3 mL NMP at 120° C. The reaction mixture was diluted with MeOH and purified by preparative HPLC-MS. The fractions containing the product were combined and freeze-dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629137B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-0cb4ee30558d4aefbf2ec5d2a9976fad |
| Source note | uspto-grants-2014_01 |