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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469390Generated: October 31, 2026

Bms-973013 → HCID 25269459, compound

https://huagongshe.com/reaction/469390

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBms-973013HCID 22293182—
ReactantHCID 58181155HCID 58181155—
SolventMethanolHCID 887—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 25269459HCID 25269459—

Reaction Steps

0.40 g (1.8 mmol) 1-piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one and 0.18 g (0.60 mmol) 6-(2-chloro-pyridine-4-carbonyl)-3,4-dimethyl-3H-benzoxazol-2-one were stirred overnight in 3 mL NMP at 120° C. The reaction mixture was diluted with MeOH and purified by preparative HPLC-MS. The fractions containing the product were combined and freeze-dried.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629137B2
Source datasetuspto-grants-2014_01
ORD IDord-0cb4ee30558d4aefbf2ec5d2a9976fad
Source noteuspto-grants-2014_01