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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 46941Generated: October 25, 2026

Phenol → 4-Hydroxyphenylglycine

https://huagongshe.com/reaction/46941

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
ReactantAmmonium AcetateHCID 517165—
ReactantPotassium glyoxylateHCID 23669142—
SolventWaterHCID 962—
Product4-HydroxyphenylglycineHCID 9214333.6%

Reaction Steps

42.1 g of potassium glyoxylate, 75 g of ammonium acetate, 60 g of phenol and 130 ml of water are treated in the same manner as described in Example 1. The reaction was conducted for a period of 24 hours. 18.1 g of DL-p-hydroxyphenylglycine are thereby obtained as crystals. Yield 33.6%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04175206
Source datasetuspto-grants-1979_11
ORD IDord-8f6516e5171a4007993cfba8ee8e628f
Source noteuspto-grants-1979_11