Aniline → HCID 58557005, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of aniline (0.30 ml, 3.27 mmol), 6-methoxypyridin-3-ylboronic acid (500 mg, 3.27 mmol) and 2-oxoacetic acid hydrate (301 mg, 3.27 mmol) in acetonitrile (20 ml) was heated under microwave irradiation at 100° C. for 1 hour. The reaction mixture was evaporated to dryness, and the crude product was triturated with acetonitrile. The solid was collected by suction filtration to get 2-(6-methoxypyridin-3-yl)-2-(phenylamino)acetic acid (202 mg, 23% yield).

Provenance & Evidence