1-Adamantaneacetic acid → HCID 53237496, compound

HRID 469536Notes

Reaction equation

HRID 469536 reaction equation
[NH2:1][N:2]1[N:11]=[C:10]([Cl:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]1=[O:13].[C:14]12([CH2:24][C:25](O)=[O:26])[CH2:23][CH:18]3[CH2:19][CH:20]([CH2:22][CH:16]([CH2:17]3)[CH2:15]1)[CH2:21]2>>[C:14]12([CH2:24][C:25]([NH:1][N:2]3[N:11]=[C:10]([Cl:12])[C:9]4[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=4)[C:3]3=[O:13])=[O:26])[CH2:21][CH:20]3[CH2:19][CH:18]([CH2:17][CH:16]([CH2:22]3)[CH2:15]1)[CH2:23]2

Participants

3

Reactant 2

HCID 1232211-Adamantaneacetic acidHCID 67160580HCID 67160580, compound

Product 1

HCID 53237496HCID 53237496, compound

Procedure

The product from Example 19A and adamantyl acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.54-1.76 (m, 12H) 1.96 (s, 3H) 2.05 (s, 2H) 7.92-8.20 (m, 3H) 8.37 (d, J=7.63 Hz, 1H) 11.20-11.50 (m, 1H); MS (ESI) m/z 372 (M+H)+.

Sources & evidence

ORD record
ord-4a2cf6dc57c444eaa494f079d9041a1e
Source dataset
uspto-grants-2014_01
Patent number
US08629143B2

Reaction notes

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