1-Adamantaneacetic acid → 2-(1-adamantyl)-N-(7-oxo-4-phenylthieno[2,3-d]pyridazin-6(7H)-yl)acetamide

Participants

Reaction Steps

The product from Example 29B and 2-(adamant-1-yl)acetic acid was processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 1.52-1.81 (m, 12H) 1.95 (s, 3H) 2.07 (s, 2H) 7.46-7.64 (m, 4H) 7.71 (dd, J=7.48, 1.98 Hz, 2H) 8.35 (d, J=5.49 Hz, 1H) 11.36 (s, 1H); MS (ESI) m/z 420 (M+H)+.

Provenance & Evidence