2-(4-Fluorophenyl)acetic acid → 2-(4-fluorophenyl)-N-(7-oxo-4-phenylthieno[2,3-d]pyridazin-6(7H)-yl)acetamide

Participants

Reaction Steps

The product from Example 29B and 2-(4-fluorophenyl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 3.71 (s, 2H) 7.18 (t, J=8.85 Hz, 2H) 7.41 (dd, J=8.54, 5.80 Hz, 2H) 7.48-7.65 (m, 4H) 7.63-7.78 (m, 2H) 8.36 (d, J=5.19 Hz, 1H) 11.80 (s, 1 H); MS (ESI) m/z 380 (M+H)+.

Provenance & Evidence