Cyclopentylacetic acid → 2-cyclopentyl-N-[1-oxo-4-(trifluoromethyl)phthalazin-2(1H)-yl]acetamide

참여 물질

역할	이름	HCID	투입량
반응물	Cyclopentylacetic acid	HCID 71606	—
반응물	2-amino-4-(trifluoromethyl)phthalazin-1(2H)-one	HCID 67161111	—
생성물	2-cyclopentyl-N-[1-oxo-4-(trifluoromethyl)phthalazin-2(1H)-yl]acetamide	HCID 53238204	—

반응 단계

The product of Example 11B and 2-cyclopentylacetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.56-11.57 (m, 1H), 8.43 (d, J=8.5 Hz, 1H), 8.11-8.17 (m, 1H), 8.04-8.08 (m, 1H), 8.00-8.05 (m, 1H), 2.34 (d, J=7.4 Hz, 2H), 2.16-2.28 (m, 1H), 1.77-1.86 (m, 2H), 1.57-1.66 (m, 2H), 1.48-1.57 (m, 2H), 1.21-1.32 (m, 2H); MS (ESI) m/z 340 (M+H)+.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08629143B2
출처 데이터셋	uspto-grants-2014_01
ORD ID	ord-8f9c274f0f4e41dd96ea0d065d4d016f
출처 메모	uspto-grants-2014_01