[(1S,2S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl]acetic acid → HCID 67160943, compound

Participants

Reaction Steps

The product of Example 67A and 2-((1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ 11.13 (s, 1H), 8.34-8.28 (m, 1H), 8.00-7.93 (m, 1H), 7.92-7.83 (m, 2H), 6.22 (dd, J=5.7, 3.0, 1H), 6.07 (dd, J=5.7, 2.9, 1H), 4.10-3.99 (m, 1H), 2.91 (s, 1H), 2.79 (s, 1H), 2.49-2.42 (m, 1H), 2.41-2.22 (m, 4H), 2.14-2.02 (m, 3H), 1.95-1.87 (m, 1H), 1.86-1.77 (m, 1H), 1.39-1.31 (m, 1H), 1.26 (d, J=8.0, 1H), 0.61 (ddd, J=11.5, 4.2, 2.6, 1H); MS (ESI) m/z 350 (M+H)+.

Provenance & Evidence