3,5-Difluorophenylacetic acid → HCID 67161443, compound

Participants

Reaction Steps

The product of Example 74A and 2-(3,5-difluorophenyl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.60-11.61 (bs, 1H), 8.34 (dd, J=7.9, 1.4 Hz, 1H), 8.13 (d, J=8.2 Hz, 1H), 8.00 (ddd, J=8.1, 7.2, 1.5 Hz, 1H), 7.90 (ddd, J=8.0, 7.1, 1.0 Hz, 1H), 7.07-7.22 (m, 3H), 3.75 (s, 2H), 3.26 (d, J=10.3 Hz, 1H), 1.89-1.93 (m, 2H), 1.79-1.83 (m, 2H), 1.70-1.76 (m, 1H), 1.39-1.58 (m, 4H), 1.19-1.32 (m, 1H); MS (ESI) m/z 398 (M+H)+.

Provenance & Evidence