Phenylacetyl chloride → N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-phenylacetamide

Participants

Role	Name	HCID	Charge
Reactant	Phenylacetyl chloride	HCID 7679	—
Reactant	2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-one	HCID 67161367	—
Product	N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-phenylacetamide	HCID 53239329	—

Reaction Steps

The product of Example 86A and 2-phenylacetyl chloride were treated as in Example 53 to give the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.70 (s, 1H), 8.39-8.44 (m, 1H), 7.85-8.05 (m, 2H), 7.69-7.76 (m, 1H), 7.59-7.66 (m, 4H), 7.21-7.41 (m, 5H), 3.69 (s, 2H); MS (ESI+) M/Z 390 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08629143B2
Source dataset	uspto-grants-2014_01
ORD ID	ord-5c53e872dea44982a0be829b49f751f4
Source note	uspto-grants-2014_01