HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(3,5-Dimethylphenyl)acetic acid → N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(3,5-dimethylphenyl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(3,5-Dimethylphenyl)acetic acid | HCID 4749495 | — |
| Edukt | 2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-one | HCID 67161367 | — |
| Produkt | N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(3,5-dimethylphenyl)acetamide | HCID 53239111 | — |
Reaktionsschritte
The product of Example 86A and 2-(3,5-dimethylphenyl)acetic acid were treated using a method similar to that described in Example 57 to give the title compound. 1H NMR (500 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.41-8.43 (m, 1H), 7.93-8.04 (m, 2H), 7.72-7.74 (m, 1H), 7.59-7.69 (m, 4H), 6.98-6.99 (bs, 2H), 6.90-6.91 (bs, 1H), 3.60 (s, 2H), 2.26 (s, 6H); MS (ESI−) M/Z 416 (M−H)−.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08629143B2 |
| Quelldatensatz | uspto-grants-2014_01 |
| ORD ID | ord-299861c7b00c499e8853254b35253e10 |
| Quellennotiz | uspto-grants-2014_01 |