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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 469598Erstellt: 25. Oktober 2026

2-(3,5-Dimethylphenyl)acetic acid → N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(3,5-dimethylphenyl)acetamide

https://huagongshe.com/reaction/469598

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(3,5-Dimethylphenyl)acetic acidHCID 4749495—
Edukt2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-oneHCID 67161367—
ProduktN-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(3,5-dimethylphenyl)acetamideHCID 53239111—

Reaktionsschritte

The product of Example 86A and 2-(3,5-dimethylphenyl)acetic acid were treated using a method similar to that described in Example 57 to give the title compound. 1H NMR (500 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.41-8.43 (m, 1H), 7.93-8.04 (m, 2H), 7.72-7.74 (m, 1H), 7.59-7.69 (m, 4H), 6.98-6.99 (bs, 2H), 6.90-6.91 (bs, 1H), 3.60 (s, 2H), 2.26 (s, 6H); MS (ESI−) M/Z 416 (M−H)−.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08629143B2
Quelldatensatzuspto-grants-2014_01
ORD IDord-299861c7b00c499e8853254b35253e10
Quellennotizuspto-grants-2014_01