(4-Methylphenyl)-1-(2H)-phthalazinone → 2-amino-4-(4-methylphenyl)-phthalazin-1(2H)-one

HRID 469629Notes

Reaction equation

HRID 469629 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11](=[O:18])[NH:10][N:9]=2)=[CH:4][CH:3]=1.C1(P(O[NH2:34])(C2C=CC=CC=2)=O)C=CC=CC=1>>[NH2:34][N:10]1[N:9]=[C:8]([C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=2)[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]1=[O:18]

Participants

3

Reactant 2

HCID 689106(4-Methylphenyl)-1-(2H)-phthalazinoneHCID 10955453O-(Diphenylphosphinyl)hydroxylamine

Product 1

HCID 671623252-amino-4-(4-methylphenyl)-phthalazin-1(2H)-one

Procedure

4-(4-methylphenyl)-phthalazin-1(2H)-one was treated with O-(diphenylphosphoryl)hydroxylamine using a method similar to that described in Example 1B to give the title compound. MS (APCI+) M/Z 252 (M+H)+.

Sources & evidence

ORD record
ord-082d6bc5be1b425a9fff591ff3585f62
Source dataset
uspto-grants-2014_01
Patent number
US08629143B2

Reaction notes

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