[(1S,2S,4S)-Bicyclo[2.2.1]hept-5-en-2-yl]acetic acid → HCID 67161451, compound

Participants

Reaction Steps

The product of Example 147A and 2-[(1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl]acetic acid were treated using a method similar to that described in Example 17C, followed by treatment with hydrogen similar to that described in Example 66 to give the title compound. 1H NMR (400 MHz, DMSO) δ 11.41-11.35 (m, 1H), 8.45-8.38 (m, 1H), 8.01-7.91 (m, 4H), 7.88-7.81 (m, 2H), 7.76-7.70 (m, 1H), 2.37-2.30 (m, 2H), 2.28-2.22 (m, 1H), 2.22-2.13 (m, 2H), 1.82-1.72 (m, 1H), 1.62-1.43 (m, 2H), 1.39-1.29 (m, 2H), 1.29-1.21 (m, 1H), 1.19-1.08 (m, 1H), 0.79-0.70 (m, 1H); MS (DCI+) M/Z 459 (M+NH4)+.

Provenance & Evidence