1-Adamantaneacetyl chloride → HCID 53236389, compound

Participants

Reaction Steps

The product of Example 163A and 2-(adamantan-1-yl)acetyl chloride were treated using a method similar to that described in Example 1C to give the title compound. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.24 (s, 1H), 8.39-8.42 (m, 1H), 7.88-8.01 (m, 2H), 7.75 (dd, J=6.9, 2.1 Hz, 1H), 7.29-7.35 (m, 3H), 3.56 (s, 1H), 2.33 (s, 2H), 2.32 (s, 3H), 2.05 (d, J=3.0 Hz, 2H), 1.93-1.97 (m, 3H), 1.54-1.72 (m, 12H); MS (APCI+) M/Z 442 (M+H)+.

Provenance & Evidence