1-Adamantaneacetyl chloride → HCID 67160633, compound

Participants

Reaction Steps

The product from Example 174A and 2-(adamant-1-yl)acetyl chloride were treated using a method similar to that described in Example 53 to give the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.28 (s, 1H), 8.50 (d, J=2.1 Hz, 1H), 8.14 (dd, J=8.6, 2.2 Hz, 1H), 7.70 (d, J=8.7 Hz, 1H), 7.51-7.55 (m, 2H), 7.11-7.15 (m, 2H), 3.85 (s, 3H), 2.05 (s, 2H), 1.92-1.98 (bs, 3H), 1.58-1.70 (m, 12H); MS (ESI+) M/Z, 524 (M+H)+.

Provenance & Evidence