2-(3,5-Difluorophenyl)acetyl chloride → HCID 67159879, compound

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Reaction Steps

The product from Example 174A and 2-(3,5-difluorophenyl)acetyl chloride were treated using a method similar to that described in Example 53 to give the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 11.77-11.80 (bs, 1H), 8.49 (d, J=2.1 Hz, 1H), 8.15 (dd, J=8.6, 2.2 Hz, 1H), 7.70 (d, J=8.7 Hz, 1H), 7.51-7.55 (m, 2H), 7.06-7.22 (m, 5H), 3.85 (s, 3H), 3.76-3.77 (bs, 2H); MS (ESI+) M/Z 503 (M+H)+.

Provenance & Evidence