2-(3-Hydroxyadamantan-1-yl)acetic acid → 2-(3-hydroxyadamantan-1-yl)-N-(7-oxo-4-phenylthieno[2,3-d]pyridazin-6(7H)-yl)acetamide

Participants

Reaction Steps

The product from Example 29B and 2-(3-hydroxyadamantan-1-yl)acetic acid were processed using a method similar to that described in Example 17C to afford the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 11.37 (s, 1H), 8.35 (d, J=5.2 Hz, 1H), 7.70-7.73 (m, 2H), 7.56-7.58 (m, 4H), 4.39 (s, 1H), 2.12 (s, 2H), 2.07-2.12 (m, 2H), 1.41-1.62 (m, 12H); MS (APCI+) M/Z 436 (M+H)+.

Provenance & Evidence