1-Chloro-4-acetoxynonane → 4-(4-Acetyl-8-hydroxy-12-methyltridecyl)benzoic acid

HRID 46967Notes

Reaction equation

HRID 46967 reaction equation
[C:1]([CH:4]([CH2:17][CH2:18][CH2:19][CH:20]([OH:26])[CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:5][CH2:6][CH2:7][C:8]1[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=1)(=[O:3])[CH3:2].Cl[CH2:28]CCC(OC(=O)C)CCCC(C)C.ClCCCC(OC(=O)C)CCCCC>>[C:1]([CH:4]([CH2:17][CH2:18][CH2:19][CH:20]([OH:26])[CH2:21][CH2:22][CH2:23][CH:24]([CH3:28])[CH3:25])[CH2:5][CH2:6][CH2:7][C:8]1[CH:9]=[CH:10][C:11]([C:12]([OH:14])=[O:13])=[CH:15][CH:16]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 3

HCID 131047161-Chloro-4-acetoxynonaneHCID 203860491-Chloro-4-acetoxy-8-methylnonaneHCID 203860504-(4-Acetyl-8-hydroxytridecyl)benzoic acid

Product 1

HCID 203861044-(4-Acetyl-8-hydroxy-12-methyltridecyl)benzoic acid

Procedure

This compound is prepared by the method described in Example 1 for 4-(4-acetyl-8-hydroxytridecyl)benzoic acid except that in Step D an equivalent quantity of 1-chloro-4-acetoxy-8-methylnonane is substituted for 1-chloro-4-acetoxynonane. The intermediates and final product thus obtained are, Step D: ethyl 4-(4-acetyl-4-tert-butoxycarbonyl-8-acetoxy-12-methyltridecyl)benzoate; Step E: ethyl 4-(4-acetyl-8-acetoxy-12-methyltridecyl)benzoate; and Step F: 4-(4-Acetyl-8-hydroxy-12-methyltridecyl)benzoic acid.

Workup

  1. customThis compound is prepared by the method

Sources & evidence

ORD record
ord-5886be96ed4e44bf9b9a3af57d69020d
Source dataset
uspto-grants-1979_11
Patent number
US04175203

Reaction notes

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