HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-6-hydrazinopyridine → tert-Butyl 3-(2-(6-bromopyridin-2-yl)hydrazono)-9-azabicyclo[3.3.1]nonane-9-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-6-hydrazinopyridine | HCID 19392588 | — |
| Reactant | N-Boc-9-azabicyclo[3.3.1]nonan-3-one | HCID 45790088 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | tert-Butyl 3-(2-(6-bromopyridin-2-yl)hydrazono)-9-azabicyclo[3.3.1]nonane-9-carboxylate | HCID 58092251 | 100% |
Reaction Steps
2-Bromo-6-hydrazinylpyridine (393 mg, 2.09 mmol) and tert-butyl 3-oxo-9-azabicyclo[3.3.1]nonane-9-carboxylate (500 mg, 2.09 mmol) were heated at reflux in EtOH (5 mL) for 16 h and the mixture concentrated to provide the title compound (855 mg, 100%) as a yellow solid: ESI MS m/z 409 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629158B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-829ac8bf9f6f458888ad37ef8b3fbbbd |
| Source note | uspto-grants-2014_01 |