Trifluoroacetic acid → HCID 67466356, compound

Participants

Reaction Steps

A solution of 20% trifluoroacetic acid in methylene chloride (20 mL) is added to [(S)-2-(3-tert-butyl-isoxazol-5-ylcarbamoyl)-pyrrolidin-1-yl]-acetic acid tert-butyl ester (0.23 g; 0.654 mmol) and the reaction mixture is stirred at room temperature overnight. After this time, the mixture is concentrated in vacuo and purified by preparative HPLC to afford title compound. ESI m/z 296 [M+H]+/294 [M−H]−

Provenance & Evidence