HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine → 5-cyclohex-1-enyl-6-(2,2,2-trifluoro-ethoxy)-N-(3-trifluoromethyl-[1,2,4]oxadiazol-5-ylmethyl)-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine | HCID 55263061 | — |
| Reactant | 5-Cyclohex-1-enyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71294107 | — |
| Product | 5-cyclohex-1-enyl-6-(2,2,2-trifluoro-ethoxy)-N-(3-trifluoromethyl-[1,2,4]oxadiazol-5-ylmethyl)-nicotinamide | HCID 71509171 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1b using 5-cyclohex-1-enyl-6-(2,2,2-trifluoroethoxy)nicotinic acid (Example 2b) and 3-(trifluoromethyl)-1,2,4-oxadiazole-5-methanamine (944905-93-5) as starting materials; MS (ESI) 451.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629166B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-4d6ace2291c746cc9f374798d1c877b8 |
| Source note | uspto-grants-2014_01 |