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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469780Generated: October 25, 2026

Aminopyridazine → 5-Cyclopentyl-N-pyridazin-3-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide

https://huagongshe.com/reaction/469780

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminopyridazineHCID 230373—
Reactant5-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acidHCID 71294186—
Product5-Cyclopentyl-N-pyridazin-3-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamideHCID 71294344—

Reaction Steps

The title compound was synthesized in analogy to Example 1b using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 9c) and 3-pyridazinamine (CAN 5469-70-5) as starting materials; MS (ESI) 367.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629166B2
Source datasetuspto-grants-2014_01
ORD IDord-20f978b0ea2148cb9dbba0f5b734de2c
Source noteuspto-grants-2014_01