(3-Methyl-1,2,4-oxadiazol-5-yl)methanamine → 5-cyclohexyl-N-(3-methyl-[1,2,4]oxadiazol-5-ylmethyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinamide

Participants

Reaction Steps

This compound was prepared following the same procedure as described in Example 11 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 4b) (100 mg, 0.33 mmol) and 3-methyl-1,2,4-oxadiazole-5-methanamine (CAN 90928-92-0) (37 mg, 0.33 mmol) as starting materials; off white solid (30 mg, 22.9%). MS (ESI): 399 (M+H)+.

Provenance & Evidence