HCID 66678705, compound → HCID 71293962, compound

HRID 469790Notes

Reaction equation

HRID 469790 reaction equation
[CH:1]1([C:6]2[C:7]([O:15][CH2:16][C:17]([F:20])([F:19])[F:18])=[N:8][CH:9]=[C:10]([CH:14]=2)[C:11]([OH:13])=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:21]1([CH2:24][N:25]2[CH:29]=[CH:28][C:27]([CH2:30][NH2:31])=[N:26]2)[CH2:23][CH2:22]1>>[CH:1]1([C:6]2[C:7]([O:15][CH2:16][C:17]([F:20])([F:19])[F:18])=[N:8][CH:9]=[C:10]([CH:14]=2)[C:11]([NH:31][CH2:30][C:27]2[CH:28]=[CH:29][N:25]([CH2:24][CH:21]3[CH2:23][CH2:22]3)[N:26]=2)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 66678705HCID 66678705, compoundHCID 712941865-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid

Product 1

HCID 71293962HCID 71293962, compound

Procedure

This compound was prepared following the same procedure as described in Example 11 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 9c) (100 mg, 0.35 mmol) and C-(1-cyclopropylmethyl-1H-pyrazol-3-yl)-methylamine (53 mg, 0.35 mmol) as starting materials; off white solid (60 mg, 41.1%). MS (ESI): 423 (M+H)+.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-bf5be1e5b436428d9188d1d3070a844c
Source dataset
uspto-grants-2014_01
Patent number
US08629166B2

Reaction notes

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