HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrimidin-5-amine → HCID 71294207, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrimidin-5-amine | HCID 344373 | — |
| Reactant | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| Product | HCID 71294207 | HCID 71294207 | — |
Reaction Steps
This compound was prepared following the same procedure as described in Example 11 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 4b) (100 mg, 0.33 mmol) and 5-pyrimidinamine (CAN 591-55-9, 31.4 mg, 0.33 mmol) as starting materials; off white solid (64 mg, 51.0%). MS (ESI): 381.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629166B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-e2e4513544ad4003b54776832872877d |
| Source note | uspto-grants-2014_01 |