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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469794Generated: October 30, 2026

4-Aminopyrimidine → HCID 71294482, compound

https://huagongshe.com/reaction/469794

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminopyrimidineHCID 68958—
Reactant5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acidHCID 71293952—
ProductHCID 71294482HCID 71294482—

Reaction Steps

This compound was prepared following the same procedure as described in Example 11 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 4b) (100 mg, 0.33 mmol) and 4-pyrimidinamine (CAN 591-54-8, 31.4 mg, 0.33 mmol) as starting materials; off white solid (50 mg, 39.8%). MS (ESI): 381.4 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629166B2
Source datasetuspto-grants-2014_01
ORD IDord-2d4a7f8d837445f6a130f38d3718f394
Source noteuspto-grants-2014_01