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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 469795Generated: October 30, 2026

Pyrimidin-5-amine → HCID 71294401, compound

https://huagongshe.com/reaction/469795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrimidin-5-amineHCID 344373—
Reactant5-Cyclopentyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acidHCID 71294186—
ProductHCID 71294401HCID 71294401—

Reaction Steps

This compound was prepared following the same procedure as described in Example 11 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 9c) (100 mg, 0.35 mmol) and 5-pyrimidinamine (CAN 591-55-9, 39.5 mg, 0.41 mmol) as starting materials; off white solid (61 mg, 48.2%). MS (ESI): 367.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08629166B2
Source datasetuspto-grants-2014_01
ORD IDord-1d77838b402e4203afae450056f9246a
Source noteuspto-grants-2014_01