Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → 2-Amino-6-bromophenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 2-Bromo-6-nitrophenol | HCID 13545453 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-Amino-6-bromophenol | HCID 15531506 | — |
반응 단계
A solution of 5.3 g (22.7 mmol) 2-bromo-6-nitro-phenol in 100 ml MeOH:THF=1:1 is hydrogenated in the presence of 0.2 g Ra—Ni (in EtOH, Degussa B113W). The reaction mixture is filtered (2 glass fiber filters used) and the filtrate is concentrated in vacuo to afford the crude title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08629168B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-26bd5e9dcb284bcea424992ae7e1b2c8 |
| 출처 메모 | uspto-grants-2014_01 |