反应详情

A solution of ethyl o-(bromomethyl)cinnamate (94.1 g., 0.35 mole), and sodium cyanide (20.6 g., 0.42 mole) in ethanol (450 ml.) is heated at reflux for 3 hours. About half of the ethanol is removed at reduced pressure. To the residue is added 500 ml. of water. The oily product is taken up in ether, washed with water, and dried over magnesium sulfate. Evaporation of the ether affords the title compound as an oil.

1. temperatureat reflux for 3 hours
2. customAbout half of the ethanol is removed at reduced pressure
3. additionTo the residue is added 500 ml
4. washwashed with water
5. dry with materialdried over magnesium sulfate
6. customEvaporation of the ether