HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Methoxycarbonyl)benzeneboronic acid → 2-tert-Butyl-4-(3-methoxycarbonylphenyl)-5-aminophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Methoxycarbonyl)benzeneboronic acid | HCID 2734714 | — |
| Reactant | 2-Tert-butyl-4-bromo-5-nitrophenol | HCID 57470236 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2-tert-Butyl-4-(3-methoxycarbonylphenyl)-5-aminophenol | HCID 57470244 | — |
Reaction Steps
2-tert-Butyl-4-(3-methoxycarbonylphenyl)-5-aminophenol (C-17) was synthesized following the general scheme above starting from 2-tert-butyl-4-bromo-5-nitrophenol (C-14-a) and 3-(methoxycarbonyl)phenylboronic acid. HPLC ret. time 2.70 min, 10-99% CH3CN, 5 min run; ESI-MS 300.5 m/z (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08629162B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-42d7610a699844ad999e52f110550ba8 |
| Source note | uspto-grants-2014_01 |