HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 470159Generated: October 25, 2026
Triethylamine → 4-[N-(3-Methoxy-benzoyl)-hydrazino]-7-methyl-2-oxo-1,5-diphenyl-1,2,5,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
https://huagongshe.com/reaction/470159
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | m-Anisohydrazide | HCID 79848 | — |
| Reactant | 4-Chloro-7-methyl-2-oxo-1,5-diphenyl-1,2,5,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | HCID 67514848 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-[N-(3-Methoxy-benzoyl)-hydrazino]-7-methyl-2-oxo-1,5-diphenyl-1,2,5,8-tetrahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | HCID 67969325 | — |
Reaction Steps
The compound of step 6 (100 mg, 0.237 mmol) was taken in 2 ml EtOH and treated successively with m-anisic hydrazide (99.6 mg, 0.6 mmol) and TEA (Triethylamine) (35 microl, 0.25 mmol) at room temperature and stirred at 60° C. for 72 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08629272B2 |
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| Source dataset | uspto-grants-2014_01 |
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| ORD ID | ord-f9f018ebeb474dff84a404c8b1998c16 |
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| Source note | uspto-grants-2014_01 |
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