反应详情

Boc-Pro-Gln-Gly-OBzl (4.0 g, 8.2 m mol) was dissolved in 90% methanol (60 ml), and hydrogen gas was passed through the solution in the presence of a spoonful of Pd-C for 6 hours. After removing the catalyst by filtration, the filtrate was concentrated under reduced pressure, and the residue was solidified by the addition of ether and recrystallized from methanol-ether.

1. customfor 6 hours
2. customAfter removing the catalyst
3. filtrationby filtration
4. concentrationthe filtrate was concentrated under reduced pressure
5. additionthe residue was solidified by the addition of ether
6. customrecrystallized from methanol-ether