HRID47035

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：NC(=O)CC[C@H](NC(=O)[C@@H]1CCCN1c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)NCC(=O)O

HCID90474469

未命名化合物

结构：CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H](CCCNC(=N)N[N+](=O)[O-])C(=O)OCc1ccccc1

HCID178455971

未命名化合物

PRODUCTS

生成物

结构：CC[C@H](C)[C@H](Nc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@H](CCCNC(=N)N[N+](=O)[O-])C(=O)OCc1ccccc1

HCID178455889

未命名化合物

PROCEDURE

实验过程

Boc-Ile-Ala-Gly-D-Arg(NO2)-OBzl (900 mg, 1.4 m mol) was demasked with respect to the N-masking group, and coupled with DNP-Pro-Gln-Gly-OH (580 mg, 1.4 m mol) in the manner similar to that of Example 1, paragraph 7).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3e94378c851341e7aaa1fd6b0c1fb2a2
来源数据集: uspto-grants-1979_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04176009
来源说明: uspto-grants-1979_11

反应 SMILES

[NH:1](C(OC(C)(C)C)=O)[C@H:2]([C:7]([NH:9][C@H:10]([C:12]([NH:14][CH2:15][C:16]([NH:18][C@@H:19]([C:30]([O:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)=[O:31])[CH2:20][CH2:21][CH2:22][NH:23][C:24](=[NH:29])[NH:25][N+:26]([O-:28])=[O:27])=[O:17])=[O:13])[CH3:11])=[O:8])[C@H:3]([CH2:5][CH3:6])[CH3:4].N1([C:68]2[CH:79]=[CH:78][C:74]([N+:75]([O-:77])=[O:76])=[CH:73][C:69]=2[N+:70]([O-:72])=[O:71])CCC[C@H]1C(N[C@H](C(NCC(O)=O)=O)CCC(=O)N)=O>>[NH:1]([C:68]1[CH:79]=[CH:78][C:74]([N+:75]([O-:77])=[O:76])=[CH:73][C:69]=1[N+:70]([O-:72])=[O:71])[C@H:2]([C:7]([NH:9][C@H:10]([C:12]([NH:14][CH2:15][C:16]([NH:18][C@@H:19]([C:30]([O:32][CH2:33][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1)=[O:31])[CH2:20][CH2:21][CH2:22][NH:23][C:24](=[NH:29])[NH:25][N+:26]([O-:28])=[O:27])=[O:17])=[O:13])[CH3:11])=[O:8])[C@H:3]([CH2:5][CH3:6])[CH3:4]