1,3-Cyclohexadiene → HCID 59784882, compound

Participants

Reaction Steps

To a solution of 4-(1,1-difluoro-2-morpholin-4-yl-ethyl)-2-methyl-6-nitro-phenylamine (60 mg, 0.2 mmol) in THF (5 mL) was added Raney nickel (100 mg) and cyclohexadiene (0.5 mL). TLC indicated the formation of the product after the reaction mixture was stirred for 3.5 h). The reaction mixture was filtered over Celite and evaporated to afforded crude title product that was used for the next step reaction without purification.

Provenance & Evidence