HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → L-alanine ethylamide hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | (S)-2-(Cbz-amino)-N-ethylpropanamide | HCID 13749958 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | L-alanine ethylamide hydrobromide | HCID 86736706 | — |
Reaction Steps
10 g (0.04 mol) of N-benzyloxycarbonyl-L-alanine ethylamide were stirred for 1 hour in 50 ml of 4-N hydrobromic acid in acetic acid. To the solution were added 300 ml of dry ether and, after stirring for a few minutes, the white solid was allowed to settle and the ether decanted from the solid. The yield of L-alanine ethylamide hydrobromide obtained was 8.0 g (96.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04176116 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-2beb01e8e4fc4a2eb2007f3d503b0ac7 |
| Source note | uspto-grants-1979_11 |